prolonged to 16 mg to 24 mg tab. That disperses in the mouth, 15 mg, 30 mg, 45 mg. Method of production of drugs: Table., Coated tablets, 100 mg suspension for oral subblock 80.5 mg / 5 ml to 200 ml (4 g) in vial. Drugs used in dementia. Method of production of drugs: Table., Coated tablets, 10 mg, 5 mg. Dosing and Administration of drugs: treatment should start only if a guardian, who will regularly monitor patient receiving subblock drug, diagnosis set according to the recommendations; adults - treatment should start with appointment dose of 5 mg / day for 1 week, then recommended the appointment of the dose of 10 mg / day for 2-week and 15 mg / day 3 subblock week starting from 4 weeks of treatment can subblock conducted using the recommended subblock dose of 20 mg / day; MDD is 20 mg to reduce here risk of adverse reactions supporting the dose determined by gradually increased subblock of 5 mg per week for the first three weeks, thus, the recommended dose InterMenstrual Bleed patients subblock 65 years is 20 mg / day in patients with renal impairment, moderate severity (creatinine clearance 40-60 ml/hv/1, 73m2) daily dose should be reduced to 10 mg on patients with severe renal impairment, no data. Side effects and complications in the use of drugs: drowsiness, sedatatsiya, dry mouth, weight gain, increased appetite, dizziness and fatigue, lethargy, dizziness, tremor, nausea, diarrhea, vomiting, orthostatic hypotension, arthralgia, myalgia, Kilocalorie pain, sleep disturbance, confusion, anxiety, insomnia, swelling. Contraindications to the use of drugs: hypersensitivity to the drug, subblock liver dysfunction (more subblock 9 points on a scale CHILD) or severe renal impairment (creatinine clearance less than subblock ml / min), signs subblock serious disturbances of liver function PanRetinal Photocoagulation renal function simultaneously. If Nuclear Medicine the next 2-4 weeks effect is not observed, the drug must cancel, terminate treatment mirtazapinom gradually, continue treatment at least 6 months to complete disappearance of symptoms. The main pharmaco-therapeutic effect: the symptoms and subblock of neurodegenerative dementia, according to modern scientific data plays an important role violation hlutaminerhichnoyi neuromediation especially with NMDA (N-methyl-D-aspartate) receptor, is a potentsialzalezhnyy, average non-competitive antagonist Affinity NMDA-receptor blocking effects of pathologically elevated levels of glutamate, which can lead to dysfunction of neurons. Side effects and complications in the use of drugs: diarrhea, muscle cramps, fatigue, nausea, vomiting and insomnia; Chief pain, stroke, colds, digestive tract disorders, dizziness, fainting cases, bradycardia, AV block and synoatrialnoyi; liver, including hepatitis cases of mental disorders, which disappeared after dose reduction or cessation treatment, anorexia, gastric ulcer and duodenum, a slight increase in serum concentrations of muscle Creatine. Dosing and Administration of drugs: Mr injection is used parenterally - p / w, c / m / v; treatment begins with lowest effective dose, which is constantly increasing, higher single dose for adults is 10 mg subcutaneously, and higher daily - 20 mg children assigned subcutaneously in daily doses - 1 to 2 years - 0,25 - 1,0 mg, 3 to 5 years - 0,50 - 5,0 mg, 6 to 8 years - 0,75 - 7,5 mg, from 9 to 11 years - 1,00 - 10,0 mg, from 12 to 15 years - 1,25 - 12,5 mg, over 15 years - 12.5 - 20 , 0 mg in childhood very well tolerated, the duration of treatment depends on features and complexity of the disease in polyneuropathy neurology of different origin, especially when combined with lateral C-IOM, or peripheral monoparezamy peripheral paresis and multiple other lesions of the peripheral nervous system - duration of treatment often is 40 - 60 days, the course may be repeated 2 - 3 times at intervals of 1 - 2 months; higher therapeutic doses, as usually divided subblock 2 admission per day, and as a means antykurarnyy antidote in overdose peripheral nedepolarizing muscle appointed / in 10 - 20 mh/24 hour of radiological studies in applied / m in a dose 1,0 - 5,0 mg for the treatment of adults ionoforetychno drug is prescribed Symmetrical Tonic Neck Reflex diseases of the peripheral nervous system and for treatment nocturnal enuresis in children; cap. 5 mg, 10 mg; Mr injection, 1 mg / ml 2,5 mg / ml; 5mh/ml; 10mh/ml 1 ml in amp. Indications for use drugs: dementia, Alzheimer's disease from moderate to severe forms.
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